CIATEJ Colección : http://ciatej.repositorioinstitucional.mx/jspui/handle/1023/14 2024-11-27T03:24:41Z Parkinson’s disease: an update on preclinical studies of induced pluripotent stem cells http://ciatej.repositorioinstitucional.mx/jspui/handle/1023/900 Título : Parkinson’s disease: an update on preclinical studies of induced pluripotent stem cells Autor: Valeria Valadez Barba; Karen Jaqueline Juárez Navarro; Eduardo Padilla Camberos; NESTOR FABIAN DIAZ MARTINEZ; JOSE RAUL GUERRA MORA; NESTOR EMMANUEL DIAZ MARTINEZ Editor: Elsevier España, S.L.U. Resumen o descripción: "Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease among adults worldwide. It is characterised by the death of dopaminergic neurons in the substantia nigra pars compacta and, in some cases, presence of intracytoplasmic inclusions of α-synuclein, called Lewy bodies, a pathognomonic sign of the disease. Clinical diagnosis of PD is based on the presence of motor alterations. The treatments currently available have no neuroprotective effect. The exact causes of PD are poorly understood. Therefore, more precise preclinical models have been developed in recent years that use induced pluripotent stem cells (iPSC). In vitro studies can provide new information on PD pathogenesis and may help to identify new therapeutic targets or to develop new drugs". 2023-01-01T00:00:00Z Comparative Analysis between Conventional PI and Fuzzy Logic PI Controllers for Indoor Benzene Concentrations http://ciatej.repositorioinstitucional.mx/jspui/handle/1023/881 Título : Comparative Analysis between Conventional PI and Fuzzy Logic PI Controllers for Indoor Benzene Concentrations Autor: NUN PITALUA DIAZ; Enrique J Herrera López; Guillermo Valencia-Palomo; Alvaro González-Angeles; Ricardo Alberto Rodríguez-Carvajal; Nohe Ramon Cazarez_Castro Resumen o descripción: "Exposure to hazardous concentrations of volatile organic compounds indoors in small workshops could affect the health of workers, resulting in respirative diseases, severe intoxication or even cancer. Controlling the concentration of volatile organic compounds is required to prevent harmful conditions for workers in indoor environments. In this document, PI and fuzzy PI controllers were used to reduce hazardous indoor air benzene concentrations in small workplaces. The workshop is represented by means of a well-mixed room model. From the knowledge obtained from the model, PI and fuzzy PI controllers were designed and their performances were compared. Both controllers were able to maintain the benzene concentration within secure levels for the workers. The fuzzy PI controller performed more efficiently than the PI controller. Both approaches could be expanded to control multiple extractor fans in order to reduce the air pollution in a shorter time. The results from the comparative analysis showed that implementing a fuzzy logic PI controller is promising for assuring indoor air quality in this kind of hazardous work environment". 2015-05-04T00:00:00Z Monitoring Lipase/Esterase Activity by Stopped Flow in a Sequential Injection Analysis System Using p-Nitrophenyl Butyrate http://ciatej.repositorioinstitucional.mx/jspui/handle/1023/876 Título : Monitoring Lipase/Esterase Activity by Stopped Flow in a Sequential Injection Analysis System Using p-Nitrophenyl Butyrate Autor: Maria del Mar Baeza Labat; Georgina Sandoval; Enrique J Herrera López; Jorge Enrique Pliego Sandoval; JUAN CARLOS MATEOS DIAZ; Jorge Alberto Rodríguez González; Francisco Valero; Alejandro Ricardo Femat Flores; Rosa María Camacho Ruíz Resumen o descripción: "Lipases and esterases are biocatalysts used at the laboratory and industrial level. To obtain the maximum yield in a bioprocess, it is important to measure key variables, such as enzymatic activity. The conventional method for monitoring hydrolytic activity is to take out a sample from the bioreactor to be analyzed off-line at the laboratory. The disadvantage of this approach is the long time required to recover the information from the process, hindering the possibility to develop control systems. New strategies to monitor lipase/esterase activity are necessary. In this context and in the first approach, we proposed a lab-made sequential injection analysis system to analyze off-line samples from shake flasks. Lipase/esterase activity was determined using p-nitrophenyl butyrate as the substrate. The sequential injection analysis allowed us to measure the hydrolytic activity from a sample without dilution in a linear range from 0.05–1.60 U/mL, with the capability to reach sample dilutions up to 1000 times, a sampling frequency of five samples/h, with a kinetic reaction of 5 min and a relative standard deviation of 8.75%. The results are promising to monitor lipase/esterase activity in real time, in which optimization and control strategies can be designed". 2015-01-27T00:00:00Z Efecto del aceite de Krill sobre las convulsiones inducidas por hipertermia experimental en ratas neonatas http://ciatej.repositorioinstitucional.mx/jspui/handle/1023/873 Título : Efecto del aceite de Krill sobre las convulsiones inducidas por hipertermia experimental en ratas neonatas Autor: LEOPOLDO EDUARDO FLORES MANCILLA; LAURA GUADALUPE MEDINA CEJA; Alejandro Arturo Canales Aguirre; ALBERTO MORALES VILLAGRAN Resumen o descripción: "Las convulsiones por fiebre ocurren en niños y pudieran provocar epilepsia, se han reportado beneficios del aceite de Krill, producto marino abundante en grasas omega-3, pero se desconoce el efecto sobre la hiperexcitabilidad neuronal temprana. Objetivo, evaluar el efecto del aceite de Krill (AK) sobre convulsiones inducidas por hipertermia experimental en ratas de 5 días de edad. El grupo Krill de crías cuyas madres consumieron dieta base (DB) más AK, se comparó con el grupo Palma crías cuyas madres consumieron DB más aceite de palma, y el grupo CTRL, crías cuyas madres consumieron DB más agua bidestilada. El grupo Krill mostró mayor resistencia a alta temperatura corporal, menos crisis mioclónicas, menores eventos y mayor latencia para la pérdida del control de la postura al comparar con los grupos Palma y CTRL (p<0.05). Conclusión.-se siguiere que el AK puede atenuar un proceso de hiperexcitabilidad temprana en el sistema nervioso central". 2016-01-01T00:00:00Z
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<description>Título : Parkinson’s disease: an update on preclinical studies of induced pluripotent stem cells Autor: Valeria Valadez Barba; Karen Jaqueline Juárez Navarro; Eduardo Padilla Camberos; NESTOR FABIAN DIAZ MARTINEZ; JOSE RAUL GUERRA MORA; NESTOR EMMANUEL DIAZ MARTINEZ Editor: Elsevier España, S.L.U. Resumen o descripción: "Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease among adults worldwide. It is characterised by the death of dopaminergic neurons in the substantia nigra pars compacta and, in some cases, presence of intracytoplasmic inclusions of α-synuclein, called Lewy bodies, a pathognomonic sign of the disease. Clinical diagnosis of PD is based on the presence of motor alterations. The treatments currently available have no neuroprotective effect. The exact causes of PD are poorly understood. Therefore, more precise preclinical models have been developed in recent years that use induced pluripotent stem cells (iPSC). In vitro studies can provide new information on PD pathogenesis and may help to identify new therapeutic targets or to develop new drugs".</description>
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<description>Título : Comparative Analysis between Conventional PI and Fuzzy Logic PI Controllers for Indoor Benzene Concentrations Autor: NUN PITALUA DIAZ; Enrique J Herrera López; Guillermo Valencia-Palomo; Alvaro González-Angeles; Ricardo Alberto Rodríguez-Carvajal; Nohe Ramon Cazarez_Castro Resumen o descripción: "Exposure to hazardous concentrations of volatile organic compounds indoors in small workshops could affect the health of workers, resulting in respirative diseases, severe intoxication or even cancer. Controlling the concentration of volatile organic compounds is required to prevent harmful conditions for workers in indoor environments. In this document, PI and fuzzy PI controllers were used to reduce hazardous indoor air benzene concentrations in small workplaces. The workshop is represented by means of a well-mixed room model. From the knowledge obtained from the model, PI and fuzzy PI controllers were designed and their performances were compared. Both controllers were able to maintain the benzene concentration within secure levels for the workers. The fuzzy PI controller performed more efficiently than the PI controller. Both approaches could be expanded to control multiple extractor fans in order to reduce the air pollution in a shorter time. The results from the comparative analysis showed that implementing a fuzzy logic PI controller is promising for assuring indoor air quality in this kind of hazardous work environment".</description>
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<description>Título : Monitoring Lipase/Esterase Activity by Stopped Flow in a Sequential Injection Analysis System Using p-Nitrophenyl Butyrate Autor: Maria del Mar Baeza Labat; Georgina Sandoval; Enrique J Herrera López; Jorge Enrique Pliego Sandoval; JUAN CARLOS MATEOS DIAZ; Jorge Alberto Rodríguez González; Francisco Valero; Alejandro Ricardo Femat Flores; Rosa María Camacho Ruíz Resumen o descripción: "Lipases and esterases are biocatalysts used at the laboratory and industrial level. To obtain the maximum yield in a bioprocess, it is important to measure key variables, such as enzymatic activity. The conventional method for monitoring hydrolytic activity is to take out a sample from the bioreactor to be analyzed off-line at the laboratory. The disadvantage of this approach is the long time required to recover the information from the process, hindering the possibility to develop control systems. New strategies to monitor lipase/esterase activity are necessary. In this context and in the first approach, we proposed a lab-made sequential injection analysis system to analyze off-line samples from shake flasks. Lipase/esterase activity was determined using p-nitrophenyl butyrate as the substrate. The sequential injection analysis allowed us to measure the hydrolytic activity from a sample without dilution in a linear range from 0.05–1.60 U/mL, with the capability to reach sample dilutions up to 1000 times, a sampling frequency of five samples/h, with a kinetic reaction of 5 min and a relative standard deviation of 8.75%. The results are promising to monitor lipase/esterase activity in real time, in which optimization and control strategies can be designed".</description>
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<title>Efecto del aceite de Krill sobre las convulsiones inducidas por hipertermia experimental en ratas neonatas</title>
<link>http://ciatej.repositorioinstitucional.mx/jspui/handle/1023/873</link>
<description>Título : Efecto del aceite de Krill sobre las convulsiones inducidas por hipertermia experimental en ratas neonatas Autor: LEOPOLDO EDUARDO FLORES MANCILLA; LAURA GUADALUPE MEDINA CEJA; Alejandro Arturo Canales Aguirre; ALBERTO MORALES VILLAGRAN Resumen o descripción: "Las convulsiones por fiebre ocurren en niños y pudieran provocar epilepsia, se han reportado beneficios del aceite de Krill, producto marino abundante en grasas omega-3, pero se desconoce el efecto sobre la hiperexcitabilidad neuronal temprana. Objetivo, evaluar el efecto del aceite de Krill (AK) sobre convulsiones inducidas por hipertermia experimental en ratas de 5 días de edad. El grupo Krill de crías cuyas madres consumieron dieta base (DB) más AK, se comparó con el grupo Palma crías cuyas madres consumieron DB más aceite de palma, y el grupo CTRL, crías cuyas madres consumieron DB más agua bidestilada. El grupo Krill mostró mayor resistencia a alta temperatura corporal, menos crisis mioclónicas, menores eventos y mayor latencia para la pérdida del control de la postura al comparar con los grupos Palma y CTRL (p<0.05). Conclusión.-se siguiere que el AK puede atenuar un proceso de hiperexcitabilidad temprana en el sistema nervioso central".</description>
<dc:date>2016-01-01T00:00:00Z</dc:date>
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