Please use this identifier to cite or link to this item: http://ciatej.repositorioinstitucional.mx/jspui/handle/1023/295
EVALUATION OF THE INHIBITION OF CARBOHYDRATE HYDROLYZING ENZYMES, THE ANTIOXIDANT ACTIVITY, AND THE POLYPHENOLIC CONTENT OF CITRUS LIMETTA PEEL EXTRACT
Eduardo Padilla_Camberos
JOSE MIGUEL FLORES FERNANDEZ
Acceso Abierto
Atribución-NoComercial-SinDerivadas
http://dx.doi.org/10.1155/2014/121760
Type 2 diabetes mellitus is one of the most frequent causes of death in Mexico, characterized by chronic hyperglycemia. One alternative strategy for this metabolic abnormality is inhibiting the enzymes responsible for the metabolism of carbohydrates. We evaluated whether the aqueous Citrus limetta peel extract could inhibit the metabolism of carbohydrates. We found that this extract inhibited primarily the enzyme 𝛼-amylase by 49.6% at a concentration of 20mg/mL and to a lesser extent the enzyme 𝛼- glucosidase with an inhibition of 28.2% at the same concentration. This inhibition is likely due to the high polyphenol content in the Citrus limetta peel (19.1mgGAE/g). Antioxidant activity of the Citrus limetta peel demonstrated dose-dependent antioxidant activity, varying from 6.5% at 1.125mg/mL to 42.5% at 20mg/mL. The study of these polyphenolic compounds having both antihyperglycemic and antioxidant activities may provide a new approach to the management of type 2 diabetes mellitus.
HINDAWI PUBLISHING CORPORATION
2014
Artículo
HINDAWI PUBLISHING CORPORATION THE SCIENTIFIC WORLD JOURNAL, VOLUMEN 2014
HINDAWI PUBLISHING CORPORATION THE SCIENTIFIC WORLD JOURNAL, VOLUMEN 2014, ARTICLE ID 121760
Inglés
Investigadores
Padilla-Camberos, E., Lazcano-Díaz, E., Flores-Fernandez, J. M., Owolabi, M. S., Allen, K., & Villanueva-Rodríguez, S. (2014). Evaluation of the inhibition of carbohydrate hydrolyzing enzymes, the antioxidant activity, and the polyphenolic content of Citrus limetta peel extract. The Scientific World Journal, 2014.
BIOLOGÍA Y QUÍMICA
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