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Acute Toxicity and Genotoxic Activity of Avocado Seed Extract (Persea americana Mill., c. v. Hass | |
Eduardo Padilla_Camberos | |
JOSE MIGUEL FLORES FERNANDEZ MOISES MARTINEZ VELAZQUEZ | |
Acceso Abierto | |
Atribución-NoComercial-SinDerivadas | |
10.1155/2013/245828 | |
http://dx.doi.org/10.1155/2013/245828 | |
The use of vegetal extracts requires toxicological and genotoxic evaluations to establish and verify safety before being added to human cosmetic, pharmaceuticalmedicine, or alimentary products. Persea americana seeds have been used in traditional medicine as treatment for several diseases. In this work, the ethanolic seed extract of Persea americana was evaluated with respect to its genotoxic potential through micronucleus assay in rodents.Thefrequency of micronuclei in groups of animals treated with avocado seed extract showed no differences compared to the negative control (vehicle); therefore, it is considered that the avocado seed extract showed no genotoxic activity in the micronucleus test. | |
Hindawi Publishing Corporation | |
2013 | |
Artículo | |
The Scientific World Journal Volume 2013, Article ID 245828, 4 pages | |
Inglés | |
Investigadores | |
Padilla-Camberos, E., Martínez-Velázquez, M., Flores-Fernández, J. M., & Villanueva-Rodríguez, S. (2013). Acute toxicity and genotoxic activity of avocado seed extract (Persea americana Mill., cv Hass). The Scientific World Journal, 2013. | |
BIOLOGÍA Y QUÍMICA | |
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