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http://ciatej.repositorioinstitucional.mx/jspui/handle/1023/470| Identification of immunodominant proteins from Mannheimia haemolytica and Histophilus somni by an immunoproteomic approach | |
| RODOLFO HERNANDEZ GUTIERREZ ANGEL HILARIO ALVAREZ HERRERA ABEL GUTIERREZ ORTEGA | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| "Mannheimia haemolytica and Histophilus somni are frequently isolated from diseased cattle with bovine respiratory disease (BRD). They compromise animal lung function and the immune responses generated are not sufficient to limit infection. Identification of specific immunogenic antigens for vaccine development represents a great challenge. Immunogenic proteins were identified by immunoproteomic approach with sera from cattle immunized with a commercial cellular vaccine of M. haemolytica and H. somni. Proteins of M. haemolytica were identified as solute ABC transporter, iron-binding protein, and hypothetical protein of capsular biosynthesis. Histophilus somni proteins correspond to porin, amino acid ABC transporter, hypothetical outer membrane protein, cysteine synthase, and outer membrane protein P6. Although these antigens share strong similarities with other proteins from animal pathogens, the ABC system proteins have been associated with virulence and these proteins could be considered as potential vaccine candidates for BRD." | |
| The Canadian Journal of Veterinary Research | |
| 2015 | |
| Artículo | |
| CANADIAN JOURNAL OF VETERINARY RESEARCH. 2015 OCT;79(4):339-42 | |
| Inglés | |
| Estudiantes Investigadores Maestros | |
| CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA | |
| Aparece en las colecciones: | ARTICULOS |
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| Identification of immunodominant.pdf | 798.9 kB | Adobe PDF | Visualizar/Abrir |