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http://ciatej.repositorioinstitucional.mx/jspui/handle/1023/593| Anti-Inflammatory activity and changes in antioxidant properties of leaf and stem extracts from Vitex mollis Kunth during in vitro digestions | |
| JUAN ALFREDO MORALES DEL RIO MELESIO GUTIERREZ LOMELI MIGUEL ANGEL ROBLES GARCIA JOSE ANTONIO AGUILAR LOPEZ EUGENIA DEL CARMEN LUGO CERVANTES PEDRO JAVIER GUERRERO MEDINA SAUL RUIZ CRUZ FRANCISCO JAVIER CINCO MOROYOQUI FRANCISCO JAVIER WONG CORRAL CARMEN LIZETTE DEL TORO SANCHEZ | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| "Vitex mollis is used in traditional Mexican medicine for the treatment of some ailments. However, there are no studies on what happens to the anti-inflammatory activity or antioxidant properties and total phenolic content of leaves and stem extracts of Vitex mollis during the digestion process; hence, this is the aim of this work. Methanolic, acetonic, and hexanic extracts were obtained from both parts of the plant. Extract yields and anti-inflammatory activity (elastase inhibition) were measured. Additionally, changes in antioxidant activity (DPPH and ABTS) and total phenols content of plant extracts before and after in vitro digestion were determined. The highest elastase inhibition to prevent inflammation was presented by hexanic extracts (leaf = 94.63% and stem = 98.30%). On the other hand, the major extract yield (16.14%), antioxidant properties (ABTS = 98.51% and DPPH = 94.47% of inhibition), and total phenols (33.70mg GAE/g of dried sample) were showed by leaf methanolic extract. Finally, leaf and stem methanolic extracts presented an antioxidant activity increase of 35.25% and 27.22%, respectively, in comparison to their initial values after in vitro digestion process. All samples showed a decrease in total phenols at the end of the digestion.These results could be the basis to search for new therapeutic agents from Vitex mollis." | |
| Hindawi Publishing Corporation | |
| 2015 | |
| Artículo | |
| Evidence-Based Complementary and Alternative Medicine Volume 2015, Article ID 349235 | |
| Estudiantes Investigadores | |
| BIOLOGÍA Y QUÍMICA | |
| Aparece en las colecciones: | ARTICULOS |
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|---|---|---|---|
| Anti-Inflamatory.pdf | 1.73 MB | Adobe PDF | Visualizar/Abrir |