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http://ciatej.repositorioinstitucional.mx/jspui/handle/1023/657| Mycobacterium tuberculosis TLR-2 agonists LprA, LM and Man-LAM induce notch1 and socs3 transcription | |
| MARIO ALBERTO FLORES VALDEZ VANIA ELVIRA BONIFAZ PENA ERIKA NAHOMY MARINO MARMOLEJO CITLALLI TORNEZ BENITEZ Mabel Guzmán Rodríguez Abel Gutiérrez Ortega Letícia Santos | |
| HUGO ENRIQUE LOPEZ GONZALEZ | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| 1996-0808 | |
| "Mycobacterium tuberculosis employs a number of strategies to subvert host signaling events, leading to its persistence within macrophages. Upon infection, Mycobacterium bovis BCG induce the expression of suppressor of cytokine signaling 3 (socs3), in a Toll-like receptor 2 (TLR2)-Notch1- dependent manner. Purified phosphatidyl inositol di-mannosides (a TLR2 agonist) act as an inducer for the Notch1-socs3 pathway. This prompted us to analyze other TLR2 agonists seeking for additional molecules that may affect this pathway. We found that lipoprotein LprA, as well as glycolipids lipomannan (LM), and mannose-capped lipoarabinomannan (ManLAM) treatment of murine macrophages resulted in stimulation of notch1 and socs3 transcription". | |
| Academic Journals | |
| 2011 | |
| Artículo | |
| African Journal of Microbiology Research Vol. 5(15), pp. 2168-2172, 4 August, 2011 | |
| Inglés | |
| Beneficiarios de fondos federales y solicitantes Bibliotecarios Empresas Estudiantes Investigadores Maestros Medios de comunicación Proveedores de fondos para estudiantes | |
| Marino-Marmolejo, E. N., Tornez-Benítez, C., Bonifaz-Pentilde, V. E., Guzmán-Rodríguez, M., López-González, H. E., Gutierrez-Ortega, A., ... & Flores-Valdez, M. A. (2011). Mycobacterium tuberculosis TLR2 agonists LprA, LM and Man-LAM induce notch1 and socs3 transcription. African Journal of Microbiology Research, 5(15), 2168-2172. | |
| BIOLOGÍA Y QUÍMICA | |
| Aparece en las colecciones: | ARTICULOS |
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