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HOW CAN WE DIAGNOSE TUBERCULOSIS MORE EFFECTIVELY? | |
MARIO ALBERTO FLORES VALDEZ | |
Acceso Abierto | |
Atribución-NoComercial-SinDerivadas | |
10.3389/frym.2018.00036 | |
"Tuberculosis (TB) is a contagious disease that can be transmitted from a person who has the bacteria Mycobacterium tuberculosis within their lungs, and who expels the bacteria by coughing, allowing TB to infect other susceptible people. TB can affect people of all ages, from kids to the elderly, and in infected people, it often spreads to other organs, in addition to the lungs and can even spread throughout the body. Today, the most common way to diagnose TB is by staining the bacteria present in sputum (coughed up mucus) samples, using a chemical that will color those bacterial cells. However, in cases where the bacteria are located outside the lungs, this strategy is not effective. Furthermore, in some cases where coughed up mucus can be obtained, it could contain too few bacteria to easily detect them. Also, there are some people in which M. tuberculosis remains “dormant” or hiding, without causing trouble, but upon weakening of the immune (defense) system, the bacteria “wake up” and cause disease. Because of these complications, new strategies for diagnosis of TB rely on the use of samples other than coughed up mucus, in which M. tuberculosis can be detected using simple tests. In this article, I discuss how the immune response varies from person to person and even within the same person, how the immune response to M. tuberculosis changes with age or other circumstances, and how we could take advantage of these changes to improve diagnosis of TB." | |
2018-08 | |
Artículo | |
Frontiers for Young Minds. 6:36. | |
Inglés | |
Bibliotecarios Estudiantes Investigadores | |
Flores-Valdez M (2018) How Can We Diagnose Tuberculosis More Effectively?. Front. Young Minds. 6:36. doi: 10.3389/frym.2018.00036 | |
CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA | |
Versión publicada | |
publishedVersion - Versión publicada | |
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