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Seasonal Effect on the Biological Activities of Litsea glaucescens Kunth Extract | |
JULIO CESAR LOPEZ ROMERO Humberto González Ríos ETNA AIDA PEÑA RAMOS CARLOS ARTURO VELAZQUEZ CONTRERAS MOISES NAVARRO NAVARRO Ramón Enrique Robles Zepeda EVELIN MARTINEZ BENAVIDEZ Inocencio Higuera Ciapara CLAUDIA ISABEL VIRUES COLORADO JOSE LUIS OLIVARES ROMERO ZAIRA JULIETA DOMINGUEZ ESQUIVEL Javier Hernández Martínez | |
Acceso Abierto | |
Atribución-NoComercial-SinDerivadas | |
https://doi.org/10.1155/2018/2738489 | |
"Tis study shows the seasonal efect on the antioxidant, antiproliferative, and antimicrobial activities of L. glaucescens Kunth (LG) leaves extracts. Teir antioxidant activity was evaluated through the DPPH, FRAP, and ORAC assays. Teir phenolic content (PC) was determined by means of the Folin-Ciocalteu method, and the main phenolic compounds were identifed through a HPLC-DAD analysis. Antiproliferative activity was determined by MTT assay against HeLa, LS 180, M12.C3.F6, and ARPE cell lines. Antimicrobial potential was evaluated against Staphylococcus aureus and Escherichia coli using a microdilution method. All the LG extracts presented high antioxidant activity and PC, with quercitrin and epicatechin being the most abundant. Antioxidant activity and PC were afected by the season; particularly autumn (ALGE) and summer (SULGE) extracts exhibited the highest values (p < 0.05). All extracts presented moderate antiproliferative activity against the cell lines evaluated, HeLa being the most susceptible of them. However, ALGE and SULGE were the most active too. About antimicrobial activity, SULGE (MIC90 < 800 μg/mL; MIC50 < 400 μg/mL), and SLGE (MIC50 < 1000 μg/mL) showed a moderate inhibitory efect against S. aureus. Tese fndings provide new information about the seasonal efect on the PC and biological properties of LG extracts. Clearly, antioxidant activity was the most important with respect to the other two." | |
20-02-2018 | |
Artículo | |
Hindawi Evidence-Based Complementary and Alternative Medicine Volume 2018, Article ID 2738489, 11 pages | |
Inglés | |
Bibliotecarios Empresas Estudiantes Investigadores | |
López-Romero, J. C., González-Ríos, H., Peña-Ramos, A., Velazquez, C., Navarro, M., Robles-Zepeda, R., Martínez-Benavidez, E., Higuera-Ciapara, I., Virués, C., Olivares, J. L., Domínguez, Z., & Hernández, J. (2018). Seasonal Effect on the Biological Activities of Litsea glaucescens Kunth Extracts. Evidence-based Complementary and Alternative Medicine, 2018, Article 2738489. https://doi.org/10.1155/2018/2738489 | |
BIOLOGÍA Y QUÍMICA | |
Versión publicada | |
publishedVersion - Versión publicada | |
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