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Off the wall: The rhyme and reason of Neurospora crassa hyphal morphogenesis
JORGE ALBERTO VERDIN RAMOS
EDDY FRANCISCO SANCHEZ LEON HING
Adriana María Rico Ramírez
Leonora Elizabeth Martínez Núñez
ROSA AURELIA FAJARDO SOMERA
MERITXELL RIQUELME PEREZ
Acceso Abierto
Atribución-NoComercial-SinDerivadas
https://doi.org/10.1016/j.tcsw.2019.100020
"The fungal cell wall building processes are the ultimate determinants of hyphal shape. In Neurospora crassa the main cell wall components, β-1,3-glucan and chitin, are synthesized by enzymes conveyed by specialized vesicles to the hyphal tip. These vesicles follow different secretory routes, which are delicately coordinated by cargo-specific Rab GTPases until their accumulation at the Spitzenkörper. From there, the exocyst mediates the docking of secretory vesicles to the plasma membrane, where they ultimately get fused. Although significant progress has been done on the cellular mechanisms that carry cell wall synthesizing enzymes from the endoplasmic reticulum to hyphal tips, a lot of information is still missing. Here, the current knowledge on N. crassa cell wall composition and biosynthesis is presented with an emphasis on the underlying molecular and cellular secretory processes."
10-02-2019
Artículo
The Cell Surface 5 (2019) 100020
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Investigadores
Verdín, J., Sánchez-León, E., Rico-Ramírez, A. M., Martínez-Núñez, L., Fajardo-Somera, R. A., & Riquelme, M. (2019). Off the wall: The rhyme and reason of Neurospora crassa hyphal morphogenesis. Cell surface (Amsterdam, Netherlands), 5, 100020. https://doi.org/10.1016/j.tcsw.2019.100020
BIOLOGÍA Y QUÍMICA
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